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Histo-blood group antigen-binding specificities of human rotaviruses are associated with gastroenteritis but not with in vitro infection

Human strains of rotavirus A (RVAs) recognize fucosylated glycans belonging to histo-blood group antigens (HBGAs) through their spike protein VP8*. Lack of these ligands due to genetic polymorphisms is associated with resistance to gastroenteritis caused by P[8] genotype RVAs. With the aim to deline...

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Detalles Bibliográficos
Autores principales: Barbé, Laure, Le Moullac-Vaidye, Béatrice, Echasserieau, Klara, Bernardeau, Karine, Carton, Thomas, Bovin, Nicolai, Nordgren, Johan, Svensson, Lennart, Ruvoën-Clouet, Nathalie, Le Pendu, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113245/
https://www.ncbi.nlm.nih.gov/pubmed/30154494
http://dx.doi.org/10.1038/s41598-018-31005-4