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Redox-responsive self-assembly PEG nanoparticle enhanced triptolide for efficient antitumor treatment
Chemotherapy induces tumor cell death by directly damaging DNA or hindering cell mitosis. Some of the drawbacks of most chemotherapy are lack of target selectivity to tumor cells, and adverse drug reaction, which limit the treatment intensity and frequency. Herein, we synthesized the prodrug of trip...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113257/ https://www.ncbi.nlm.nih.gov/pubmed/30154488 http://dx.doi.org/10.1038/s41598-018-29692-0 |