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Redox-responsive self-assembly PEG nanoparticle enhanced triptolide for efficient antitumor treatment

Chemotherapy induces tumor cell death by directly damaging DNA or hindering cell mitosis. Some of the drawbacks of most chemotherapy are lack of target selectivity to tumor cells, and adverse drug reaction, which limit the treatment intensity and frequency. Herein, we synthesized the prodrug of trip...

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Detalles Bibliográficos
Autores principales: Wang, Yanchun, Liu, Xuewei, Wang, Xuemei, Zheng, Wei, Zhang, Junping, Shi, Feng, Liu, Junbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113257/
https://www.ncbi.nlm.nih.gov/pubmed/30154488
http://dx.doi.org/10.1038/s41598-018-29692-0