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Loss of Wwox drives metastasis in triple-negative breast cancer by JAK2/STAT3 axis

Loss of WW domain-containing oxidoreductase (Wwox) expression has been observed in breast cancer (BC). However, its regulatory effects are largely unknown, especially in triple-negative breast cancer (TNBC). Herein, gene expression profiling revealed that JAK/STAT3 pathway was one of the most differ...

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Detalles Bibliográficos
Autores principales: Chang, Renxu, Song, Lele, Xu, Yi, Wu, Yanjun, Dai, Cheng, Wang, Xinyu, Sun, Xia, Hou, Yingyong, Li, Wei, Zhan, Xianbao, Zhan, Lixing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113304/
https://www.ncbi.nlm.nih.gov/pubmed/30154439
http://dx.doi.org/10.1038/s41467-018-05852-8