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Complement regulatory protein CD46 induces autophagy against oxidative stress-mediated apoptosis in normal and asthmatic airway epithelium

Autophagy plays a major role in defending against oxidative stress in respiratory epithelial cells. The complement regulatory protein CD46 can enhance autophagy and decrease local complement activation at sites of inflammation. This study investigated the mechanism by which CD46 protects against oxi...

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Detalles Bibliográficos
Autores principales: Tsai, Yi-Giien, Wen, Yung-Sung, Wang, Jiu-Yao, Yang, Kuender D., Sun, Hai-Lun, Liou, Jia-Hung, Lin, Ching-Yuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113329/
https://www.ncbi.nlm.nih.gov/pubmed/30154478
http://dx.doi.org/10.1038/s41598-018-31317-5