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Corneal myofibroblasts inhibit regenerating nerves during wound healing

Abnormal nerve regeneration often follows corneal injury, predisposing patients to pain, dry eye and vision loss. Yet, we lack a mechanistic understanding of this process. A key event in corneal wounds is the differentiation of keratocytes into fibroblasts and scar-forming myofibroblasts. Here, we s...

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Detalles Bibliográficos
Autores principales: Jeon, Kye-Im, Hindman, Holly B., Bubel, Tracy, McDaniel, Thurma, DeMagistris, Margaret, Callan, Christine, Huxlin, Krystel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113331/
https://www.ncbi.nlm.nih.gov/pubmed/30154512
http://dx.doi.org/10.1038/s41598-018-30964-y