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Evaluation of modified Interferon alpha mRNA constructs for the treatment of non-melanoma skin cancer

Application of in vitro transcribed (IVT) messenger ribonucleic acid (mRNA) is an increasingly popular strategy to transiently produce proteins as therapeutics in a tissue or organ of choice. Here, we focused on the skin and aimed to test if whole human skin tissue explant technology can be used to...

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Detalles Bibliográficos
Autores principales: Hochmann, Sarah, Mittermeir, Michaela, Santic, Radmila, Koszik, Frieder, Griessner, Lanay, Sonderegger, Alina Sarah, Hoffmann, Thomas, Russe, Elisabeth, Scheiblhofer, Sandra, Weiss, Richard, Mandler, Markus, Schneeberger, Achim, Strunk, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113332/
https://www.ncbi.nlm.nih.gov/pubmed/30154486
http://dx.doi.org/10.1038/s41598-018-31061-w