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Human Bone Marrow-Resident Natural Killer Cells Have a Unique Transcriptional Profile and Resemble Resident Memory CD8(+) T Cells

Human lymphoid tissues harbor, in addition to CD56(bright) and CD56(dim) natural killer (NK) cells, a third NK cell population: CD69(+)CXCR6(+) lymphoid tissue (lt)NK cells. The function and development of ltNK cells remain poorly understood. In this study, we performed RNA sequencing on the three N...

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Detalles Bibliográficos
Autores principales: Melsen, Janine E., Lugthart, Gertjan, Vervat, Carly, Kielbasa, Szymon M., van der Zeeuw, Sander A. J., Buermans, Henk P. J., van Ostaijen-ten Dam, Monique M., Lankester, Arjan C., Schilham, Marco W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113396/
https://www.ncbi.nlm.nih.gov/pubmed/30186282
http://dx.doi.org/10.3389/fimmu.2018.01829