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Human Bone Marrow-Resident Natural Killer Cells Have a Unique Transcriptional Profile and Resemble Resident Memory CD8(+) T Cells
Human lymphoid tissues harbor, in addition to CD56(bright) and CD56(dim) natural killer (NK) cells, a third NK cell population: CD69(+)CXCR6(+) lymphoid tissue (lt)NK cells. The function and development of ltNK cells remain poorly understood. In this study, we performed RNA sequencing on the three N...
Autores principales: | Melsen, Janine E., Lugthart, Gertjan, Vervat, Carly, Kielbasa, Szymon M., van der Zeeuw, Sander A. J., Buermans, Henk P. J., van Ostaijen-ten Dam, Monique M., Lankester, Arjan C., Schilham, Marco W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113396/ https://www.ncbi.nlm.nih.gov/pubmed/30186282 http://dx.doi.org/10.3389/fimmu.2018.01829 |
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