High‐affinity PD‐1 molecules deliver improved interaction with PD‐L1 and PD‐L2

The inhibitory checkpoint molecule programmed death (PD)‐1 plays a vital role in maintaining immune homeostasis upon binding to its ligands, PD‐L1 and PD‐L2. Several recent studies have demonstrated that soluble PD‐1 (sPD‐1) can block the interaction between membrane PD‐1 and PD‐L1 to enhance the an...

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Detalles Bibliográficos
Autores principales: Li, Yanyan, Liang, Zhaoduan, Tian, Ye, Cai, Wenxuan, Weng, Zhiming, Chen, Lin, Zhang, Huanling, Bao, Yifeng, Zheng, Hongjun, Zeng, Sihai, Bei, Chunhua, Li, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113430/
https://www.ncbi.nlm.nih.gov/pubmed/29890018
http://dx.doi.org/10.1111/cas.13666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113430/
https://www.ncbi.nlm.nih.gov/pubmed/29890018
http://dx.doi.org/10.1111/cas.13666

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