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Oncogenic roles of enhancer of zeste homolog 1/2 in hematological malignancies

Polycomb group (PcG) proteins regulate the expression of target genes by modulating histone modifications and are representative epigenetic regulators that maintain the stemness of embryonic and hematopoietic stem cells. Histone methyltransferases enhancer of zeste homolog 1 and 2 (EZH1/2), which ar...

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Detalles Bibliográficos
Autores principales: Nakagawa, Makoto, Kitabayashi, Issay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113435/
https://www.ncbi.nlm.nih.gov/pubmed/29845708
http://dx.doi.org/10.1111/cas.13655