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Pravastatin But Not Simvastatin Improves Survival and Neurofunctional Outcome After Cardiac Arrest and Cardiopulmonary Resuscitation

Cardiac arrest (CA) followed by cardiopulmonary resuscitation (CPR) is associated with high mortality and poor neurological outcome. We compared the effects of pravastatin and simvastatin on survival and neurofunction in a murine model of CA/CPR. Pravastatin, a hydrophilic statin, increased survival...

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Detalles Bibliográficos
Autores principales: Bergt, Stefan, Grub, Andrea, Wagner, Steffen, Engelke, Hauke, Nöldge-Schomburg, Gabriele, Vollmar, Brigitte, Roesner, Jan P., Wagner, Nana-Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113548/
https://www.ncbi.nlm.nih.gov/pubmed/30167563
http://dx.doi.org/10.1016/j.jacbts.2017.01.009