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Nuclear Respiratory Factor 1 (NRF-1) Controls the Activity Dependent Transcription of the GABA-A Receptor Beta 1 Subunit Gene in Neurons

While the exact role of β1 subunit-containing GABA-A receptors (GABARs) in brain function is not well understood, altered expression of the β1 subunit gene (GABRB1) is associated with neurological and neuropsychiatric disorders. In particular, down-regulation of β1 subunit levels is observed in brai...

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Detalles Bibliográficos
Autores principales: Li, Zhuting, Cogswell, Meaghan, Hixson, Kathryn, Brooks-Kayal, Amy R., Russek, Shelley J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113564/
https://www.ncbi.nlm.nih.gov/pubmed/30186109
http://dx.doi.org/10.3389/fnmol.2018.00285