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The Metabolic Redox Regime of Pseudomonas putida Tunes Its Evolvability toward Novel Xenobiotic Substrates

During evolution of biodegradation pathways for xenobiotic compounds involving Rieske nonheme iron oxygenases, the transition toward novel substrates is frequently associated with faulty reactions. Such events release reactive oxygen species (ROS), which are endowed with high mutagenic potential. In...

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Detalles Bibliográficos
Autores principales: Akkaya, Özlem, Pérez-Pantoja, Danilo R., Calles, Belén, Nikel, Pablo I., de Lorenzo, Víctor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113623/
https://www.ncbi.nlm.nih.gov/pubmed/30154264
http://dx.doi.org/10.1128/mBio.01512-18