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Mammalian prion propagation in PrP transgenic Drosophila
Mammalian prions propagate by template-directed misfolding and aggregation of normal cellular prion related protein PrP(C) as it converts into disease-associated conformers collectively referred to as PrP(Sc). Mammalian species may be permissive for prion disease because these hosts have co-evolved...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113635/ https://www.ncbi.nlm.nih.gov/pubmed/29985975 http://dx.doi.org/10.1093/brain/awy183 |