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Ginsenoside Rb1 and Rd Remarkably Inhibited the Hepatic Uptake of Ophiopogonin D in Shenmai Injection Mediated by OATPs/oatps

Shenmai injection (SMI) is derived from traditional Chinese herbal prescription Shendong yin and widely used for treating cardiovascular diseases. Ophiopogonin D (OPD) is one of the main active components of SMI. The hepatic uptake of OPD is mediated by organic anion-transporting polypeptides (OATPs...

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Detalles Bibliográficos
Autores principales: Liu, Xiaopei, Chen, Lin, Liu, Mingyi, Zhang, Hong, Huang, Shibo, Xiong, Yuqing, Xia, Chunhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113708/
https://www.ncbi.nlm.nih.gov/pubmed/30186179
http://dx.doi.org/10.3389/fphar.2018.00957