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Stepwise triple-click functionalization of synthetic peptides

The increasing popularity of peptides as promising molecular scaffolds for biomedical applications and as valuable biochemical probes makes new methods allowing for their modification highly desirable. We describe herein an optimized protocol based on a sequence of CuAAC click reactions and selectiv...

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Detalles Bibliográficos
Autores principales: Kovalová, Anna, Pohl, Radek, Vrabel, Milan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113709/
https://www.ncbi.nlm.nih.gov/pubmed/30091427
http://dx.doi.org/10.1039/c8ob01617h