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Two isoforms of cyclic GMP-dependent kinase-I exhibit distinct expression patterns in the adult mouse dorsal root ganglion

cGMP-dependent kinase-I (cGKI) is known to regulate spinal pain processing. This enzyme consists of two isoforms (cGKIα and cGKIβ) that show distinct substrate specificity and tissue distribution. It has long been believed that the α isoform is exclusively expressed in the adult dorsal root ganglion...

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Detalles Bibliográficos
Autores principales: Uchida, Hitoshi, Matsumura, Shinji, Katano, Tayo, Watanabe, Masahiko, Schlossmann, Jens, Ito, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113733/
https://www.ncbi.nlm.nih.gov/pubmed/30152261
http://dx.doi.org/10.1177/1744806918796409