Assessment of the genetic and clinical determinants of fracture risk: genome wide association and mendelian randomisation study

OBJECTIVES: To identify the genetic determinants of fracture risk and assess the role of 15 clinical risk factors on osteoporotic fracture risk. DESIGN: Meta-analysis of genome wide association studies (GWAS) and a two-sample mendelian randomisation approach. SETTING: 25 cohorts from Europe, United...

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Detalles Bibliográficos
Autores principales: Trajanoska, Katerina, Morris, John A, Oei, Ling, Zheng, Hou-Feng, Evans, David M, Kiel, Douglas P, Ohlsson, Claes, Richards, J Brent, Rivadeneira, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group Ltd. 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113773/
https://www.ncbi.nlm.nih.gov/pubmed/30158200
http://dx.doi.org/10.1136/bmj.k3225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113773/
https://www.ncbi.nlm.nih.gov/pubmed/30158200
http://dx.doi.org/10.1136/bmj.k3225

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