Spheroid Size Does not Impact Metabolism of the β-blocker Propranolol in 3D Intestinal Fish Model

Compared to two-dimensional (2D) cell culture, cellular aggregates or spheroids (3D) offer a more appropriate alternative in vitro system where individual cell-cell communication and micro-environment more closely represent the in vivo organ; yet we understand little of the physiological conditions...

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Detalles Bibliográficos
Autores principales: Langan, Laura M., Owen, Stewart F., Trznadel, Maciej, Dodd, Nicholas J. F., Jackson, Simon K., Purcell, Wendy M., Jha, Awadhesh N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113889/
https://www.ncbi.nlm.nih.gov/pubmed/30186177
http://dx.doi.org/10.3389/fphar.2018.00947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113889/
https://www.ncbi.nlm.nih.gov/pubmed/30186177
http://dx.doi.org/10.3389/fphar.2018.00947

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