Cargando…

Spheroid Size Does not Impact Metabolism of the β-blocker Propranolol in 3D Intestinal Fish Model

Compared to two-dimensional (2D) cell culture, cellular aggregates or spheroids (3D) offer a more appropriate alternative in vitro system where individual cell-cell communication and micro-environment more closely represent the in vivo organ; yet we understand little of the physiological conditions...

Descripción completa

Detalles Bibliográficos
Autores principales:	Langan, Laura M., Owen, Stewart F., Trznadel, Maciej, Dodd, Nicholas J. F., Jackson, Simon K., Purcell, Wendy M., Jha, Awadhesh N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113889/ https://www.ncbi.nlm.nih.gov/pubmed/30186177 http://dx.doi.org/10.3389/fphar.2018.00947

Ejemplares similares

Direct Measurements of Oxygen Gradients in Spheroid Culture System Using Electron Parametric Resonance Oximetry
por: Langan, Laura M., et al.
Publicado: (2016)

Correction: Direct Measurements of Oxygen Gradients in Spheroid Culture System Using Electron Parametric Resonance Oximetry
por: Langan, Laura M., et al.
Publicado: (2016)

Application of the rainbow trout derived intestinal cell line (RTgutGC) for ecotoxicological studies: molecular and cellular responses following exposure to copper
por: Langan, Laura M., et al.
Publicado: (2017)

Establishment and long-term maintenance of primary intestinal epithelial cells cultured from the rainbow trout, Oncorhynchus mykiss
por: Langan, Laura M., et al.
Publicado: (2018)

Pharmaceutical Metabolism in Fish: Using a 3-D Hepatic In Vitro Model to Assess Clearance
por: Baron, Matthew G., et al.
Publicado: (2017)

Characteristic interactivity of landiolol, an ultra-short-acting highly selective β(1)-blocker, with biomimetic membranes: Comparisons with β(1)-selective esmolol and non-selective propranolol and alprenolol
por: Tsuchiya, Hironori, et al.
Publicado: (2013)

Propranolol Blocks Cardiac and Neuronal Voltage-Gated Sodium Channels
por: Wang, Dao W., et al.
Publicado: (2010)

The AT1 Receptor Blocker Telmisartan Reduces Intestinal Mucus Thickness in Obese Mice
por: Nickel, Laura, et al.
Publicado: (2022)

Potentiation of Morphine-Induced Antinociception by Propranolol: The Involvement of Dopamine and GABA Systems
por: Afify, Elham A., et al.
Publicado: (2017)

Mechanoenzymology in the Kinetic Resolution of β-Blockers: Propranolol as a Case Study
por: Gamboa-Velázquez, Gonzalo, et al.
Publicado: (2022)

Blockade of β-Adrenergic Receptors by Propranolol Disrupts Reconsolidation of Drug Memory and Attenuates Heroin Seeking
por: Chen, Liangpei, et al.
Publicado: (2021)

Beta-Blocker Propranolol Modulates Decision Urgency During Sequential Information Gathering
por: Hauser, Tobias U., et al.
Publicado: (2018)

Non–beta blocker enantiomers of propranolol and atenolol inhibit vasculogenesis in infantile hemangioma
por: Seebauer, Caroline T., et al.
Publicado: (2022)

Population Pharmacokinetics and Pharmacodynamics of Oral Propranolol in Pediatric Patients With Infantile Hemangioma
por: Takechi, Tomoki, et al.
Publicado: (2018)

Discovery and Development of Calcium Channel Blockers
por: Godfraind, Théophile
Publicado: (2017)

An Automated Quantification Tool for Angiogenic Sprouting From Endothelial Spheroids
por: Kannan, Pavitra, et al.
Publicado: (2022)

Efficacy of Combined Topical Timolol and Oral Propranolol for Treating Infantile Hemangioma: A Meta-Analysis of Randomized Controlled Trials
por: Qiao, Junbo, et al.
Publicado: (2020)

Increase in stable isotope ratios driven by metabolic alterations in amphipods exposed to the beta-blocker propranolol
por: Ek, Caroline, et al.
Publicado: (2019)

Beta-blockers in cardiac arrhythmias–Clinical pharmacologist’s point of view
por: Wołowiec, Łukasz, et al.
Publicado: (2023)

Nonselective β-blocker propranolol for orbital and periorbital hemangiomas in infants: a new first-line of treatment?
por: El-Essawy, Rania, et al.
Publicado: (2011)

New Insights into Cardiac and Brain Sodium Channels Modulation by Beta Blockers
por: Chahine, Mohamed
Publicado: (2011)

Ambiguities in dietary antioxidant supplementation compared to calcium channel blockers therapy
por: Godfraind, Théophile, et al.
Publicado: (2015)

The Use of Beta Blockers in Takotsubo Syndrome as Compared to Acute Coronary Syndrome
por: Kummer, Marvin, et al.
Publicado: (2020)

Therapeutic Potential of CUDC-907 (Fimepinostat) for Hepatocarcinoma Treatment Revealed by Tumor Spheroids-Based Drug Screening
por: Liao, Wei, et al.
Publicado: (2021)

Capsule Networks Showed Excellent Performance in the Classification of hERG Blockers/Nonblockers
por: Wang, Yiwei, et al.
Publicado: (2020)

Antiarrhythmic calcium channel blocker verapamil inhibits trek currents in sympathetic neurons
por: Herrera-Pérez, S., et al.
Publicado: (2022)

Functional xenobiotic metabolism and efflux transporters in trout hepatocyte spheroid cultures
por: Uchea, Chibuzor, et al.
Publicado: (2015)

The HCN Channel Blocker ZD7288 Induces Emesis in the Least Shrew (Cryptotis parva)
por: Zhong, W., et al.
Publicado: (2021)

Dihydropyridine-derived calcium channel blocker as a promising anti-hantavirus entry inhibitor
por: Wang, Bin, et al.
Publicado: (2022)

Apigenin and Luteolin Attenuate the Breaching of MDA-MB231 Breast Cancer Spheroids Through the Lymph Endothelial Barrier in Vitro
por: Hong, Junli, et al.
Publicado: (2018)

Impairment of Hypoxia-Induced CA IX by Beta-Blocker Propranolol—Impact on Progression and Metastatic Potential of Colorectal Cancer Cells
por: Barathova, Monika, et al.
Publicado: (2020)

A Novel Voltametric Measurements of Beta Blocker Drug Propranolol on Glassy Carbon Electrode Modified with Carbon Black Nanoparticles
por: Bargiel, Izabela, et al.
Publicado: (2021)

Angiotensin II Receptor Blocker Associated With Less Outcome Risk in Patients With Acute Kidney Disease
por: Wu, Vin-Cent, et al.
Publicado: (2022)

Non-selective beta-blockers and the incidence of hepatocellular carcinoma in patients with cirrhosis: a meta-analysis
por: He, Xinyi, et al.
Publicado: (2023)

Vitamin C Inhibits Metastasis of Peritoneal Tumors By Preventing Spheroid Formation in ID8 Murine Epithelial Peritoneal Cancer Model
por: Xu, Yayun, et al.
Publicado: (2020)

Digging into Lipid Membrane Permeation for Cardiac Ion Channel Blocker d-Sotalol with All-Atom Simulations
por: DeMarco, Kevin R., et al.
Publicado: (2018)

Bis-Quinolinium Cyclophane Blockers of SK Potassium Channels Are Antagonists of M3 Muscarinic Acetylcholine Receptors
por: Bugay, Vladislav, et al.
Publicado: (2020)

Dihydropyridine Calcium Channel Blockers Suppress the Transcription of PD-L1 by Inhibiting the Activation of STAT1
por: Pan, Xiaohui, et al.
Publicado: (2021)

REL-1017 (Esmethadone), A Novel NMDAR Blocker for the Treatment of MDD is Not Neurotoxic in Sprague-Dawley Rats
por: Bifari, Francesco, et al.
Publicado: (2022)

Effect of Polyplex Size on Penetration into Tumor Spheroids
por: Casadidio, Cristina, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_r4unkq1boopm0qulfus9guh4as