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Lapatinib, a Dual Inhibitor of Epidermal Growth Factor Receptor (EGFR) and HER-2, Enhances Radiosensitivity in Mouse Bladder Tumor Line-2 (MBT-2) Cells In Vitro and In Vivo

BACKGROUND: The aim of this study was to evaluate the effect of lapatinib, a dual inhibitor of epidermal growth factor receptor (EGFR) and HER-2, on the radiosensitivity of murine bladder tumor line-2 (MBT-2) cells in vitro and in vivo. MATERIAL/METHODS: MBT-2 cells were pretreated with lapatinib at...

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Detalles Bibliográficos
Autores principales: Mu, Yi, Sun, Deyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113922/
https://www.ncbi.nlm.nih.gov/pubmed/30125265
http://dx.doi.org/10.12659/MSM.909865