Quick and sustained clinical response to MEK inhibitor I in a NF1 patient with neurofibromas

Neurofibromatosis 1 (NF1) is an autosomal dominant tumour predisposition disorder with a birth incidence of about 1 in 2,700 and prevalence of 1 in 4,560. The NF1 gene codes for an ubiquitous protein: neurofibromin. Neurofibromin interacts with the proto-oncogene RAS to suppress tumour formation. In...

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Detalles Bibliográficos
Autores principales: Papalia, Honoré, Audic, Frédérique, Rivière, Gabriel Revon, Verschuur, Arnauld, André, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cancer Intelligence 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113984/
https://www.ncbi.nlm.nih.gov/pubmed/30174724
http://dx.doi.org/10.3332/ecancer.2018.862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113984/
https://www.ncbi.nlm.nih.gov/pubmed/30174724
http://dx.doi.org/10.3332/ecancer.2018.862

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