A Controlled Release System for Long-Acting Intravitreal Delivery of Small Molecules

PURPOSE: The short half lives of small molecules in the vitreous requires frequent repeated intravitreal injections that are impractical for treatment of chronic eye diseases. We sought to develop a method for increasing the intravitreal half-life of small-molecule drugs. METHODS: We adapted a techn...

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Detalles Bibliográficos
Autores principales: Machinaga, Nobuo, Ashley, Gary W., Reid, Ralph, Yamasaki, Atsushi, Tanaka, Kyosuke, Nakamura, Koichi, Yabe, Yoshiyuki, Yoshigae, Yasushi, Santi, Daniel V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114027/
https://www.ncbi.nlm.nih.gov/pubmed/30174998
http://dx.doi.org/10.1167/tvst.7.4.21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114027/
https://www.ncbi.nlm.nih.gov/pubmed/30174998
http://dx.doi.org/10.1167/tvst.7.4.21

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