Discovery of ebselen as an inhibitor of Cryptosporidium parvum glucose-6-phosphate isomerase (CpGPI) by high-throughput screening of existing drugs

Cryptosporidium parvum is a water-borne and food-borne apicomplexan pathogen. It is one of the top four diarrheal-causing pathogens in children under the age of five in developing countries, and an opportunistic pathogen in immunocompromised individuals. Unlike other apicomplexans, C. parvum lacks K...

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Detalles Bibliográficos
Autores principales: Eltahan, Rana, Guo, Fengguang, Zhang, Haili, Xiang, Lixin, Zhu, Guan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114080/
https://www.ncbi.nlm.nih.gov/pubmed/29414105
http://dx.doi.org/10.1016/j.ijpddr.2018.01.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114080/
https://www.ncbi.nlm.nih.gov/pubmed/29414105
http://dx.doi.org/10.1016/j.ijpddr.2018.01.003

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