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P-glycoprotein-9 and macrocyclic lactone resistance status in selected strains of the ovine gastrointestinal nematode, Teladorsagia circumcincta

The Teladorsagia circumcincta P-glycoprotein-9 (Tci-pgp-9) gene has previously been implicated in multiple-anthelmintic resistance in this parasite. Here we further characterise genetic diversity in Tci-pgp-9 and its possible role in ivermectin (IVM) and multi-drug resistance using two UK field isol...

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Detalles Bibliográficos
Autores principales: Turnbull, Frank, Jonsson, Nicholas N., Kenyon, Fiona, Skuce, Philip J., Bisset, Stewart A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114102/
https://www.ncbi.nlm.nih.gov/pubmed/29414109
http://dx.doi.org/10.1016/j.ijpddr.2018.01.004