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Profiling G protein-coupled receptors of Fasciola hepatica identifies orphan rhodopsins unique to phylum Platyhelminthes

G protein-coupled receptors (GPCRs) are established drug targets. Despite their considerable appeal as targets for next-generation anthelmintics, poor understanding of their diversity and function in parasitic helminths has thwarted progress towards GPCR-targeted anti-parasite drugs. This study faci...

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Detalles Bibliográficos
Autores principales: McVeigh, Paul, McCammick, Erin, McCusker, Paul, Wells, Duncan, Hodgkinson, Jane, Paterson, Steve, Mousley, Angela, Marks, Nikki J., Maule, Aaron G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114109/
https://www.ncbi.nlm.nih.gov/pubmed/29474932
http://dx.doi.org/10.1016/j.ijpddr.2018.01.001