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Profiling G protein-coupled receptors of Fasciola hepatica identifies orphan rhodopsins unique to phylum Platyhelminthes
G protein-coupled receptors (GPCRs) are established drug targets. Despite their considerable appeal as targets for next-generation anthelmintics, poor understanding of their diversity and function in parasitic helminths has thwarted progress towards GPCR-targeted anti-parasite drugs. This study faci...
Autores principales: | McVeigh, Paul, McCammick, Erin, McCusker, Paul, Wells, Duncan, Hodgkinson, Jane, Paterson, Steve, Mousley, Angela, Marks, Nikki J., Maule, Aaron G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114109/ https://www.ncbi.nlm.nih.gov/pubmed/29474932 http://dx.doi.org/10.1016/j.ijpddr.2018.01.001 |
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