Multiple imputation for patient reported outcome measures in randomised controlled trials: advantages and disadvantages of imputing at the item, subscale or composite score level

BACKGROUND: Missing data can introduce bias in the results of randomised controlled trials (RCTs), but are typically unavoidable in pragmatic clinical research, especially when patient reported outcome measures (PROMs) are used. Traditionally applied to the composite PROMs score of multi-item instru...

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Detalles Bibliográficos
Autores principales: Rombach, Ines, Gray, Alastair M., Jenkinson, Crispin, Murray, David W., Rivero-Arias, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114240/
https://www.ncbi.nlm.nih.gov/pubmed/30153796
http://dx.doi.org/10.1186/s12874-018-0542-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114240/
https://www.ncbi.nlm.nih.gov/pubmed/30153796
http://dx.doi.org/10.1186/s12874-018-0542-6

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