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The ensemble diversity of non-coding RNA structure is lower than random sequence

In addition to energetically optimal structures, RNAs can fold into near energy suboptimal conformations that may be populated and play functional roles. The diversity of this structural ensemble can be estimated using a metric derived from the calculated RNA partition function: the ensemble diversi...

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Detalles Bibliográficos
Autor principal: Moss, Walter N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114264/
https://www.ncbi.nlm.nih.gov/pubmed/30175283
http://dx.doi.org/10.1016/j.ncrna.2018.04.005