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Genome-wide association study for variants that modulate relationships between cerebrospinal fluid amyloid-beta 42, tau, and p-tau levels

BACKGROUND: A relationship quantitative trait locus exists when the correlation between multiple traits varies by genotype for that locus. Relationship quantitative trait loci (rQTL) are often involved in gene-by-gene (G×G) interactions or gene-by-environmental interactions, making them a powerful t...

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Detalles Bibliográficos
Autores principales: Maxwell, Taylor J., Corcoran, Chris, del-Aguila, Jorge L., Budde, John P., Deming, Yuetiva, Cruchaga, Carlos, Goate, Alison M., Kauwe, John S. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114488/
https://www.ncbi.nlm.nih.gov/pubmed/30153862
http://dx.doi.org/10.1186/s13195-018-0410-y