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Fibroblast growth factor 21 inhibits atherosclerosis in apoE−/− mice by ameliorating Fas-mediated apoptosis

BACKGROUND: FGF21 is a critical endogenous regulator in energy homeostasis and systemic glucose and lipid metabolism. Despite intensive study of the metabolic functions of FGF21, its important role in heart disease needs further exploration. Apoptosis induced by ox-LDL in vascular endothelial cells...

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Detalles Bibliográficos
Autores principales: Yan, Xinxin, Gou, Zhongshan, Li, Yuan, Wang, Yu, Zhu, Jingyan, Xu, Guidong, Zhang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114502/
https://www.ncbi.nlm.nih.gov/pubmed/30157856
http://dx.doi.org/10.1186/s12944-018-0846-x