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Harnessing the biological complexity of Big Data from LINCS gene expression signatures

Gene expression profiling using transcriptional drug perturbations are useful for many biomedical discovery studies including drug repurposing and elucidation of drug mechanisms (MoA) and many other pharmacogenomic applications. However, limited data availability across cell types has severely hinde...

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Detalles Bibliográficos
Autores principales: Musa, Aliyu, Tripathi, Shailesh, Kandhavelu, Meenakshisundaram, Dehmer, Matthias, Emmert-Streib, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114505/
https://www.ncbi.nlm.nih.gov/pubmed/30157183
http://dx.doi.org/10.1371/journal.pone.0201937