HMGB1 knockdown increases MM cell vulnerability by regulating autophagy and DNA damage repair

BACKGROUND: With the development of novel therapeutic agents, the survival of multiple myeloma (MM) patients has much improved. However, the disease is incurable due to drug resistance. Previous studies have found that high-mobility group box 1 (HMGB1) is involved in inflammation, angiogenesis, DNA...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Xing, He, Donghua, Zhang, Enfan, Chen, Jing, Chen, Qingxiao, Li, Yi, Yang, Li, Yang, Yang, Zhao, Yi, Wang, Gang, He, Jingsong, Cai, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114506/
https://www.ncbi.nlm.nih.gov/pubmed/30157958
http://dx.doi.org/10.1186/s13046-018-0883-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114506/
https://www.ncbi.nlm.nih.gov/pubmed/30157958
http://dx.doi.org/10.1186/s13046-018-0883-3

Ejemplares similares