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HMGB1 knockdown increases MM cell vulnerability by regulating autophagy and DNA damage repair
BACKGROUND: With the development of novel therapeutic agents, the survival of multiple myeloma (MM) patients has much improved. However, the disease is incurable due to drug resistance. Previous studies have found that high-mobility group box 1 (HMGB1) is involved in inflammation, angiogenesis, DNA...
Autores principales: | Guo, Xing, He, Donghua, Zhang, Enfan, Chen, Jing, Chen, Qingxiao, Li, Yi, Yang, Li, Yang, Yang, Zhao, Yi, Wang, Gang, He, Jingsong, Cai, Zhen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114506/ https://www.ncbi.nlm.nih.gov/pubmed/30157958 http://dx.doi.org/10.1186/s13046-018-0883-3 |
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