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Automatic evaluation of tumor budding in immunohistochemically stained colorectal carcinomas and correlation to clinical outcome

BACKGROUND: Tumor budding, meaning a detachment of tumor cells at the invasion front of colorectal carcinoma (CRC) into single cells or clusters (<=5 tumor cells), has been shown to correlate to an inferior clinical outcome by several independent studies. Therefore, it has been discussed as a com...

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Detalles Bibliográficos
Autores principales: Weis, Cleo-Aron, Kather, Jakob Nikolas, Melchers, Susanne, Al-ahmdi, Hanaa, Pollheimer, Marion J., Langner, Cord, Gaiser, Timo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114534/
https://www.ncbi.nlm.nih.gov/pubmed/30153844
http://dx.doi.org/10.1186/s13000-018-0739-3