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The c-Myc-regulated lncRNA NEAT1 and paraspeckles modulate imatinib-induced apoptosis in CML cells

Chronic myeloid leukemia (CML) is a clonal disease characterized by the presence of the constitutively active tyrosine kinase BCR-ABL oncoprotein. Although BCR-ABL is crucially important for pathogenesis and treatment response, it is thought that some additional factors might be involved in the regu...

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Detalles Bibliográficos
Autores principales: Zeng, Chengwu, Liu, Sichu, Lu, Shuai, Yu, Xibao, Lai, Jing, Wu, Yifan, Chen, Shaohua, Wang, Liang, Yu, Zhi, Luo, Gengxin, Li, Yangqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114538/
https://www.ncbi.nlm.nih.gov/pubmed/30153828
http://dx.doi.org/10.1186/s12943-018-0884-z