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Increased epigenetic age in normal breast tissue from luminal breast cancer patients

BACKGROUND: Age is one of the most important risk factors for developing breast cancer. However, age-related changes in normal breast tissue that potentially lead to breast cancer are incompletely understood. Quantifying tissue-level DNA methylation can contribute to understanding these processes. W...

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Detalles Bibliográficos
Autores principales: Hofstatter, Erin W., Horvath, Steve, Dalela, Disha, Gupta, Piyush, Chagpar, Anees B., Wali, Vikram B., Bossuyt, Veerle, Storniolo, Anna Maria, Hatzis, Christos, Patwardhan, Gauri, Von Wahlde, Marie-Kristin, Butler, Meghan, Epstein, Lianne, Stavris, Karen, Sturrock, Tracy, Au, Alexander, Kwei, Stephanie, Pusztai, Lajos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114717/
https://www.ncbi.nlm.nih.gov/pubmed/30157950
http://dx.doi.org/10.1186/s13148-018-0534-8