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HSP90AA1-mediated autophagy promotes drug resistance in osteosarcoma
BACKGROUND: Osteosarcoma is the most common primary bone tumor in children and adolescents. Unfortunately, osteosarcoma treatments often fail due to the development of chemoresistance, of which the underlying molecular mechanisms still remain unclear. In this study, we demonstrated that HSP90AA1 gen...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114771/ https://www.ncbi.nlm.nih.gov/pubmed/30153855 http://dx.doi.org/10.1186/s13046-018-0880-6 |