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Ubiquitin-conjugating enzyme UBE2J1 negatively modulates interferon pathway and promotes RNA virus infection

BACKGROUND: Viral infection activates innate immune pathways and interferons (IFNs) play a pivotal role in the outcome of a viral infection. Ubiquitin modifications of host and viral proteins significantly influence the progress of virus infection. Ubiquitin-conjugating enzyme E2s (UBE2) have the ca...

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Detalles Bibliográficos
Autores principales: Feng, Tingting, Deng, Lei, Lu, Xiaochuan, Pan, Wen, Wu, Qihan, Dai, Jianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114777/
https://www.ncbi.nlm.nih.gov/pubmed/30157886
http://dx.doi.org/10.1186/s12985-018-1040-5