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Ubiquitin-conjugating enzyme UBE2J1 negatively modulates interferon pathway and promotes RNA virus infection
BACKGROUND: Viral infection activates innate immune pathways and interferons (IFNs) play a pivotal role in the outcome of a viral infection. Ubiquitin modifications of host and viral proteins significantly influence the progress of virus infection. Ubiquitin-conjugating enzyme E2s (UBE2) have the ca...
Autores principales: | Feng, Tingting, Deng, Lei, Lu, Xiaochuan, Pan, Wen, Wu, Qihan, Dai, Jianfeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114777/ https://www.ncbi.nlm.nih.gov/pubmed/30157886 http://dx.doi.org/10.1186/s12985-018-1040-5 |
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