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Epigenetic Optical Mapping of 5-Hydroxymethylcytosine in Nanochannel Arrays
[Image: see text] The epigenetic mark 5-hydroxymethylcytosine (5-hmC) is a distinct product of active DNA demethylation that is linked to gene regulation, development, and disease. In particular, 5-hmC levels dramatically decline in many cancers, potentially serving as an epigenetic biomarker. The n...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114841/ https://www.ncbi.nlm.nih.gov/pubmed/29924591 http://dx.doi.org/10.1021/acsnano.8b03023 |