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Chemotherapy-induced niche perturbs hematopoietic reconstitution in B-cell acute lymphoblastic leukemia

BACKGROUND: Considerable efforts have been devoted toward the uncovering of the molecular mechanisms underlying the maintenance of hematopoietic stem cells (HSCs) by the normal bone marrow (BM) niche. Previously, we demonstrated that a chemotherapy-induced niche, which is mainly composed of mesenchy...

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Detalles Bibliográficos
Autores principales: Tang, Chao, Li, Ming-Hao, Chen, Ya-Li, Sun, Hui-Ying, Liu, Sheng-Li, Zheng, Wei-Wei, Zhang, Meng-Yi, Li, Hui, Fu, Wei, Zhang, Wen-Jun, Liang, Ai-Bin, Tang, Zhong-Hua, Hong, Deng-Li, Zhou, Bin-Bing S., Duan, Cai-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114852/
https://www.ncbi.nlm.nih.gov/pubmed/30157922
http://dx.doi.org/10.1186/s13046-018-0859-3