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An automated screening method for detecting compounds with goitrogenic activity using transgenic zebrafish embryos
The knowledge on environmentally relevant chemicals that may interfere with thyroid signaling is scarce. Here, we present a method for the screening of goitrogens, compounds that disrupt the thyroid gland function, based on the automatic orientation of zebrafish in a glass capillary and a subsequent...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114901/ https://www.ncbi.nlm.nih.gov/pubmed/30157258 http://dx.doi.org/10.1371/journal.pone.0203087 |