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Unraveling the mechanism of the cadherin-catenin-actin catch bond

The adherens junctions between epithelial cells involve a protein complex formed by E-cadherin, β-catenin, α-catenin and F-actin. The stability of this complex was a puzzle for many years, since in vitro studies could reconstitute various stable subsets of the individual proteins, but never the enti...

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Detalles Bibliográficos
Autores principales: Adhikari, Shishir, Moran, Jacob, Weddle, Christopher, Hinczewski, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114904/
https://www.ncbi.nlm.nih.gov/pubmed/30118477
http://dx.doi.org/10.1371/journal.pcbi.1006399