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Single-stranded binding proteins and helicase enhance the activity of prokaryotic argonautes in vitro

Prokaryotic argonautes are a unique class of nucleic acid-guided endonucleases putatively involved in cellular defense against foreign genetic elements. While their eukaryotic homologs and Cas protein counterparts require single-stranded RNAs as guides, some prokaryotic argonautes are able to utiliz...

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Detalles Bibliográficos
Autores principales: Hunt, Eric A., Evans, Thomas C., Tanner, Nathan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114923/
https://www.ncbi.nlm.nih.gov/pubmed/30157272
http://dx.doi.org/10.1371/journal.pone.0203073