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Single-stranded binding proteins and helicase enhance the activity of prokaryotic argonautes in vitro
Prokaryotic argonautes are a unique class of nucleic acid-guided endonucleases putatively involved in cellular defense against foreign genetic elements. While their eukaryotic homologs and Cas protein counterparts require single-stranded RNAs as guides, some prokaryotic argonautes are able to utiliz...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114923/ https://www.ncbi.nlm.nih.gov/pubmed/30157272 http://dx.doi.org/10.1371/journal.pone.0203073 |