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3D hydrogel breast cancer models for studying the effects of hypoxia on epithelial to mesenchymal transition

Solid tumors are 3D assemblies of cancer cells, together with multiple stromal cell types within an extracellular matrix. Yet, the vast majority of cell-based studies to characterize oncogenesis and discovery of new anti-cancer drugs is conducted using conventional 2D monolayer culture systems, wher...

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Detalles Bibliográficos
Autores principales: Wang, Ying, Mirza, Sameer, Wu, Shaohua, Zeng, Jiping, Shi, Wen, Band, Hamid, Band, Vimla, Duan, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114943/
https://www.ncbi.nlm.nih.gov/pubmed/30181809
http://dx.doi.org/10.18632/oncotarget.25891