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3D hydrogel breast cancer models for studying the effects of hypoxia on epithelial to mesenchymal transition
Solid tumors are 3D assemblies of cancer cells, together with multiple stromal cell types within an extracellular matrix. Yet, the vast majority of cell-based studies to characterize oncogenesis and discovery of new anti-cancer drugs is conducted using conventional 2D monolayer culture systems, wher...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114943/ https://www.ncbi.nlm.nih.gov/pubmed/30181809 http://dx.doi.org/10.18632/oncotarget.25891 |