Liver metastasis of pancreatic cancer: the hepatic microenvironment impacts differentiation and self-renewal capacity of pancreatic ductal epithelial cells

Pancreatic ductal adenocarcinoma (PDAC) is often diagnosed at advanced stages with the liver as the main site of metastases. The hepatic microenvironment has been shown to determine outgrowth of liver metastases. Cancer stem cells (CSCs) are essential for initiation and maintenance of tumors and acq...

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Detalles Bibliográficos
Autores principales: Knaack, Hendrike, Lenk, Lennart, Philipp, Lisa-Marie, Miarka, Lauritz, Rahn, Sascha, Viol, Fabrice, Hauser, Charlotte, Egberts, Jan-Hendrik, Gundlach, Jan-Paul, Will, Olga, Tiwari, Sanjay, Mikulits, Wolfgang, Schumacher, Udo, Hengstler, Jan G., Sebens, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114965/
https://www.ncbi.nlm.nih.gov/pubmed/30167093
http://dx.doi.org/10.18632/oncotarget.25884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114965/
https://www.ncbi.nlm.nih.gov/pubmed/30167093
http://dx.doi.org/10.18632/oncotarget.25884

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