A comprehensive evaluation of Hippo pathway silencing in sarcomas

TAZ and YAP are transcriptional coactivators negatively regulated by the Hippo pathway that have emerged as key oncoproteins in several cancers including sarcomas. We hypothesized that loss of expression of the Hippo kinases might be a mechanism of activating TAZ and YAP. By immunohistochemistry, TA...

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Detalles Bibliográficos
Autores principales: Merritt, Nicole M., Fullenkamp, Colleen A., Hall, Sarah L., Qian, Qining, Desai, Chandni, Thomason, Jon, Lambertz, Allyn M., Dupuy, Adam J., Darbro, Benjamin, Tanas, Munir R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114978/
https://www.ncbi.nlm.nih.gov/pubmed/30167083
http://dx.doi.org/10.18632/oncotarget.25824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114978/
https://www.ncbi.nlm.nih.gov/pubmed/30167083
http://dx.doi.org/10.18632/oncotarget.25824

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