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DNA Repair Molecular Beacon assay: a platform for real-time functional analysis of cellular DNA repair capacity

Numerous studies have shown that select DNA repair enzyme activities impact response and/or toxicity of genotoxins, suggesting a requirement for enzyme functional analyses to bolster precision medicine or prevention. To address this need, we developed a DNA Repair Molecular Beacon (DRMB) platform th...

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Detalles Bibliográficos
Autores principales: Li, Jianfeng, Svilar, David, McClellan, Steven, Kim, Jung-Hyun, Ahn, Eun-Young Erin, Vens, Conchita, Wilson, David M., Sobol, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114979/
https://www.ncbi.nlm.nih.gov/pubmed/30167090
http://dx.doi.org/10.18632/oncotarget.25859