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Age-dependent dormant resident progenitors are stimulated by injury to regenerate Purkinje neurons

Outside of the neurogenic niches of the brain, postmitotic neurons have not been found to undergo efficient regeneration. We demonstrate that mouse Purkinje cells (PCs), which are born at midgestation and are crucial for development and function of cerebellar circuits, are rapidly and fully regenera...

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Detalles Bibliográficos
Autores principales: Bayin, N Sumru, Wojcinski, Alexandre, Mourton, Aurelien, Saito, Hiromitsu, Suzuki, Noboru, Joyner, Alexandra L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115187/
https://www.ncbi.nlm.nih.gov/pubmed/30091706
http://dx.doi.org/10.7554/eLife.39879